急性脑出血患者局部脑血流量的研究

Study of regional cerebral flow in patients with acute intracerebral hemorrhage

目的:研究急性脑出血(AICH)患者局部脑血流量(rCBF)的变化。方法:对88例AICH患者行脑血流单光子发射断层扫描(SPECT)显像,判定rCBF改变的部位及范围。结果:AICH患者远离出血灶的同侧、对侧大脑半球和对侧小脑半球缺血发生率分别为68.75%、31.25%、和48.75%。基底节出血最常引起皮层失联络的部位是额叶(78.5%),其次是颞叶(63%)、顶叶(58.5%)、对侧小脑(45.5%)和枕叶(25%)。肢瘫越重者发生对侧小脑失联络现象越高。结论:AICH可引起远离出血灶的大脑半球及对侧小脑半球缺血。随着病情改善,rCBF也有所恢复。

Objective：To study the changes of regional cerebral blood flow （rCBF） in patients with acute intracerebral hemorrhage（AICH） . Methods：rCBF perfusion imaging with SPECT was performed in 88 patients with AICH.The relative analysis was made in rCBF changes. Results：The rates of brain ischemia caused by AICH far away from the origin in either cerebral hemisphere and contralatera cerebellar hemisphere were 68.75%,31.25%and 48.75%respectively. The patients with basal nuclei hemorrhage had damdges in the frontal cortex mostly（78.5%）,temporal（63%）,parietal（58.5%）,occipital（25%）cortex and contralatera cerebellar hemisphere （45.5%） secondly. The hemiplegia cases damaged more seriously had more crossed cerebral-cerebellar diaschisis. Conclusion：AICH can cause brain ischemia far away from the origin in either cerebral hemisphere and contralatera cerebellar hemisphere . As AICH recovered,improvement of rCBF or return to normal are also observed.