上海市药品不良反应监测系统中4491份有效报告的分析

Analyses of 4491 valid cases report about monitoring system of the adverse drug reaction in Shanghai

目的:观察上海市近年来药品不良反应(ADR)的报告情况。方法:对本市不良反应监测中心网络呈报系统内4491例有效报告进行分析、讨论。结果:药物所致不良反应无性别、年龄差异;给药途径主要为静脉给药和口服给药(两者占87.98%);共涉及14个药物类别,其中抗感染药物居首位;累及25个系统或器官,以皮肤及其附属器损害为主(占46.25%)。结论:应重视ADR的报告与监测。

Objective：To analyse of Shanghai adverse drug reaction （ADR） reports, in recent years. Methods：4 491 valid cases reported by the ADR monitoring center network reporting system in Shanghai were analysed. Results：The occurrence of the ADR showed no difference in gender or age. The administration routes were mainly by venous or by mouth （ accounting for 87.98 % ）. The ADR referred to 14 drug categories, of which antibiotics took the first place. The ADR involved 25 systems or organs, of which the damage of skin and its appendant organs were primary （ accounting for 46.25 % ）. Conclusion：The report and monitoring of the ADR should be paid attention to.