心理干预对非糜烂性胃食管反流病患者抑郁情绪的影响

Effect of psychological intervention on depression with non-erosive reflux disease patients

目的探讨心理治疗对非糜烂性胃食管反流病（NERD）患者抑郁情绪的干预效果及其对生活质量的影响。方法将68例非糜烂性胃食管反流病患者随机分为治疗组和对照组，评定并比较2组抑郁自评量表（SDS）、健康状况问卷（SF-36）得分及其临床疗效。结果治疗4周后，治疗组SDS评分[（41．58±6．85）分]显著低于对照组[（50．42±9．26）分]（P〈0．01）；其临床疗效评定显著高于对照组（P〈0．01）；SF-36除生理机能[（86．9±11．7）分和（83．8±16．5）分]外，其他指标治疗组均优于对照组（P〈0．05）。结论心理干预能显著降低NERD患者抑郁情绪，并可提高临床疗效、躯体功能及生活质量。

Objective To explore the effects of psychotherapy on depression with non-erosive reflux disease patients and its quality of life. Methods 68 patients with non-erosive reflux disease accompanied patients were divided into treatment and control groups . The scores of SDS , SF-36 questionnaire and clinical outcome were evaluated between the two groups. Results The scores of SDS of the treatment group （41.58 ± 6.85） were significantly lower than the control group （50.42 ± 9.26） . The evaluation of clinical outcome were significantly better than the control group （ P〈0. 05 ） , while the SF-36 quality of life questionnaire scores with treatment group were significantly better than the control group except for physiological function （86.9 ± 11.7 and 83.8 ± 16.5）. Conclusion Psychological intervention could obviously decrease the degree of depression and improves clinical outcome, physiological function and quality of life with non-erosive reflux disease patients.