中西医结合综合治疗早期糖尿病肾病97例疗效观察

Effect of Chinese and Western Medicine for Early Diabetic Nephropathy:An Observation of 97 Cases

目的:观察中西医结合综合治疗早期糖尿病肾病的临床疗效。方法:将171例患者随机分为2组。对照组74例,以常规西医治疗。中西医结合组97例,在对照组治疗基础上加用桂蜡外敷双涌泉穴、中药外洗浸泡、口服仙芪地黄汤及静脉滴注疏血通注射液治疗。结果:总有效率中西医结合组为100%,对照组为90.54%,2组比较,差异有显著性意义(P<0.05)。2组治疗后24小时尿微量白蛋白(mAlb)、尿β2-MG及血液流变学指标均有降低,治疗前后比较,差异有显著性或非常显著性意义(P<0.05,P<0.01);2组治疗后24小时尿微量白蛋白、尿β2-MG及血液流变学指标比较,差异有显著性或非常显著性意义(P<0.05,P<0.01)。结论:中西医结合综合治疗早期糖尿病肾病疗效明显优于西医治疗。

Objective:To observe the therapeutic effect of Chinese and western medicine for early diabetic nephropathy(EDN).Methods:One hundred and seven- ty-one EDN patients were randomized into two groups.The control group(n=74) was given routine western medical treatment,and the combined treatment group(n= 97)received acupoint application of Guila on bilateral Yongquan,washing with herbal medicine,oral use of herbal medicine and intravenous drip of Shuxue Huoxue Tongluo Injection additionally.Results:The total effect was 100% in the combined treatment group and 90.54% in the control group(P<0.95).The 24-hour uri- nary protein,uric Beta 2 Microglobulin(β2-MG)and hemorheological parameters were decreased after treatment in the two group(P<0.05 or P<0.01 compared with those before treatment),and the difference of the above indexes in the two groups was significant(P<0.05 or P<0.01).Conclusion:The therapeutic effect of Chinese and western medicine for EDN is better than western medicine only.