摘要
目的优选地黄管食通颗粒乙醇提取的方法及制备工艺条件。方法(1)建立了冬凌草中冬凌草甲素荧光暗斑的薄层定量新方法;(2)采用正交试验法,以冬凌草中冬凌草甲素的转移率为指标,优选地黄管食通颗粒的乙醇提取工艺条件。结果最佳条件为10倍量95%乙醇回流提取3次,每次提取4h。结论该工艺可以有效提高冬凌草的提取率。
OBJECTIVE To optimize the method and condition for the. extraction process of dihuang guanshitong granule. METHODS （ 1 ） A new TLCS method was established for determination of Oridonin in Rabdosia rubescens ; （2） The optimum alcohol extracting procedure of dihuang guanshi-tong granule was selected with the content and extraction efficiency of oridonin from Rabdosia rubescens by orthogonal test design method. RESULTS The optimum alcohol extracting procedure was determined as 10 times of 95% alcohol refluxing and extracting 4h for 3 times. CONCLUSION The optimum extracting procedure can increase extraction efficiency of Rabdosia rubescens.
出处
《海峡药学》
2007年第7期17-19,共3页
Strait Pharmaceutical Journal
基金
河南省科技攻关项目(编号:0124170637)
关键词
地黄管食通颗粒
冬凌草甲素
乙醇提取
正交试验
Dihuang Guanshi-tong Granule
Oridonin
Ethanol extract
Orthogonal test design
