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HIF-1、VEGF与缺血性脑血管病 被引量：1

Hypoxia Inducible Factor-1、Vascular Endothelial Growth Factor and Cerebral Ischemia.
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摘要 世界平均脑血管病的发病率为190—200／10万，而我国高达280／10万，其死亡率超过100／10万。脑血管疾病居高不下的致残率更是影响人类提高生活质量和制约社会经济发展的巨大障碍。因此必须研究它的病理生理机制，寻找新的治疗策略。缺血性脑血管病是因血管堵塞致局部脑血流量下降，氧合营养转运障碍，最终导致组织缺氧和细胞死亡。此时机体需作出反应维持机体氧的平衡与稳态来抵抗这种不利因素。
作者 王钟秀 杨林花
机构地区 山西医科大学第二医院血液科
出处 《血栓与止血学》 2007年第4期189-192,共4页 Chinese Journal of Thrombosis and Hemostasis
关键词 缺氧诱导因子-1 血管内皮生长因子 新生血管形成
分类号 R743 [医药卫生—神经病学与精神病学]
  • 相关文献

参考文献16

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共引文献3

同被引文献16

  • 1李贻奎,宁可永,梁嵘,李连达.大鼠冠状动脉结扎心肌缺血模型方法的改进[J].中国新药杂志,2005,14(4):427-428. 被引量：51
  • 2袁淑慧,张云汉,李惠翔,高冬玲,张岚,尹玉惠.HIF-1α、VEGF的表达及微血管密度与乳腺癌生物学行为的关系[J].河南肿瘤学杂志,2005,18(3):158-160. 被引量：5
  • 3王培利,雷燕,林燕林,陈可冀.当归补血汤含药血清对培养内皮细胞生长因子受体表达的影响[J].中西医结合心脑血管病杂志,2006,4(3):209-212. 被引量：24
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二级引证文献9

血栓与止血学
2007年 第4期

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