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缬沙坦合用卡维地洛对充血性心力衰竭心功能及左室重塑的影响 被引量:1

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摘要 目的探讨缬沙坦合用卡维地洛对慢性充血性心力衰竭心功能及心室重塑的影响。方法68例充血性心力衰竭患者用随机单盲对照法分成A级和B组。A组给强心苷及利尿药常规治疗;B组在常规治疗基础上加缬沙坦及卡维地洛,疗程6个月。比较A组、B组间治疗前后心率、收缩压、6分钟步行试验及左心室舒张末期内径(LVEDD)、左心室收缩末期内径(LVESD)、左心室射血分数(LVEF)及左室质量指数(LVMI),并进行统计学分析。结果A组治疗后心率显著下降、6分钟步行试验、LVEF显著改善(P<0.05);B组治疗后心率、收缩压、LVEDD、LVESD、LVMI显著下降、6分钟步行试验及LVEF显著改善(P<0.01),与A组比较有显著意义(P<0.05;P<0.01)。结论缬沙坦合用卡维地洛改善慢性充血性心力衰竭心功能并逆转心室重塑。
出处 《心脑血管病防治》 2007年第4期261-263,共3页 CARDIO-CEREBROVASCULAR DISEASE PREVENTION AND TREATMENT
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