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RASSF1A基因甲基化与肿瘤的关系 被引量：1

The Relation between Methylation of Gene RASSF1A and Tumor
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摘要 RASSFiA（ras association domain family 1 agene）是RAS相关结构域家族似S5F1基因的转录本A，它编码一组RAS效应蛋白，它的启动子高甲基化及其基因外失活已在多种人肿瘤细胞株和原发性癌组织中普遍存在，它在多种恶性肿瘤的发生和诱导细胞凋亡的过程中发挥作用。 Ras association domain family 1 agene （RASSF1A）is transcript A of gene RASSF1. It encodes a set of effector protein of RAS. Promoter hypermethylation of RASSF1A and inactivation of RASSF1A are very popular in many tumor cell line and primary tumor tissue. It plays an important role in the formation of various malignancy tumors and inducing apoptosis of cells.
作者 李军 潘晓琳 潘泽民
机构地区 石河子大学医学院新疆地方与民族高发病省部共建教育部重点实验室
出处 《国际遗传学杂志》 CAS 2007年第4期287-289,共3页 International Journal of Genetics
基金 国家自然科学基金（30260036）
关键词 RASSF1A 甲基化 基因 肿瘤 RASSF1A Methylation Gene Tumor
分类号 R730 [医药卫生—肿瘤]
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国际遗传学杂志
2007年 第4期

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