摘要
采用免疫组织化学LSAB法,对86例无淋巴结转移的直肠腺癌p21ras的表达进行检测并分析与5年生存的关系。结果显示:在生存期<5年的24例患者中,p21ras表达阳性者20例(83.3%);在生存期≥5年的62例患者中,p21ras表达阳性者10例(16.1%)。前者的阳性表达率高于后者(P<0.01)。结果说明:无淋巴结转移的直肠腺癌p21ras的阳性表达与5年生存密切相关,这对术后制定综合性治疗方案有指导作用。
The relationship between expression of p21ras in rectal adenocarcinomas without lymph node metastasis and the 5 year survival was studied in 86 cases by LSAB immunohistochemical technique. The results showed that among 24 cases with <5 years survival the positive expression of p21ras in rectal adenocarcinomas was revealed in 20 cases (83.3%); however,among 62 cases with ≥5 years survival, 10 cases (16.1%);The former was higher than the latter in the rate of the positive expression( P <0.01).The results suggested that there was close relationship between the positive expression of p21ras in rectal adenocarcinomas without the lymph node metastasis and the 5 year survival.It plays an instructive role in making comprehensive postoperative treatment measures.
出处
《实用癌症杂志》
1997年第1期27-28,共2页
The Practical Journal of Cancer