马鞭草合剂防治放射性口腔炎的效果观察

Observation on effect of European verbena mixture to prevent and to treat patients with radioactive stomatitis

[目的]观察马鞭草合剂对放射性口腔炎的防治效果。[方法]将120例头颈部肿瘤放射治疗病人随机分为观察组、对照1组和对照2组,每组40例。观察组遵医嘱含服马鞭草合剂;对照1组遵医嘱静脉输注左氧氟沙星注射液;对照2组遵医嘱服用甘露醇口服液。[结果]2周、8周时三组间差异无统计学意义,4周、6周时观察组与对照2组差异无统计学意义,但观察组和对照2组分别与对照1组间有显著性差异。[结论]马鞭草合剂防治放射性口腔炎经济、有效、安全。

Objective： To observe the effect of European verbena mixture to prevent and to treat patients with radioactive stomatitis. Methods： A total of 120 cases of head and neck tumor patients undergoing radiotherapy were divided into test group, control group 1, and control group 2, 40 cases each. Patients of test group were given European verbena mixture buccaling. Patients of control group 1 were given levofloxac injection intravenously infusion. Patients of control group 2 were orally taken mannitol injection. Conclusion： There were no statistical significant differences among the three groups at two and eight weeks of treatment. There were no statistical significant differences between test group and control group 2 cases at four and six weeks of treatment. However, there was statistical significant difference between test group and control group 1 patients. Conclusion： It is economic, effective and safe to apply European verbenae mixture to prevent and to treat radioactive stomatitis.