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牛奶蛋白过敏致婴儿上消化道出血的临床诊治 被引量:8

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摘要 目的探讨牛奶蛋白过敏致婴儿上消化道出血的诊治经验。方法23例2~6个月患儿,临床主要表现为突发或反复的呕血或呕咖啡渣。22例患儿行电子胃镜检查观察胃内出血情况。同时行血常规、肝功能、凝血象、血清学食物过敏原检测及血清幽门螺杆菌抗体测定。结果所有患儿除有轻中度贫血外,血小板计数、凝血象、肝功能均正常,嗜酸性粒细胞正常。10例患儿血清学食物过敏原测定中5例IgE阳性;2例牛奶蛋白抗体阳性。3例患儿伴轻度低蛋白血症。22例胃镜检查结果显示:糜烂性胃炎18例;2例食管糜烂;1例十二指肠糜烂;1例十二指肠降部溃疡。胃黏膜病理学检查显示局部有嗜酸性粒细胞浸润。血清学幽门螺杆菌抗体检测阳性1例,余为阴性。饮食回避治疗及对症处理,患儿均痊愈。结论牛奶蛋白过敏在小儿中并非少见,且临床表现多样化。消化道出血是常见的表现之一。内镜下表现以胃黏膜糜烂为主。饮食回避是主要的诊断及治疗方法且疗效肯定。胃黏膜病理学检查有助于诊断。
出处 《华中医学杂志》 2007年第4期255-256,共2页 Central China Medical Journal
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参考文献6

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