甲亢女性患者血清T_3、T_4和淋巴细胞自发微核率的检测

Detection of Serum T_3 or T_4 and Spontaneous Micronucleus Ratio of Lymphocytes in Female Patients with Hyperthyriodism

本文对甲亢女性患者治疗前组和健康女性正常对照组的血清T3、T4水平及淋巴细胞微核率（MN）进行检测分析。结果显示治疗前组和正常对照组的微核率分别为3．97±2．24‰和0．97±0．74‰，治疗前组的MN明显高于正常对照组。两组的T3、T4水平亦有显著差异。说明甲亢患者具有疾病发生的遗传素质。本研究为甲亢发生的基础研究提供参考资料。

Micronucleus ratio and T3 or T4 were assayed in peripheral blood of female patients suf fering from hyperthyroidism and normal females in the control group. The results showed that the micronucleus ratio was 3. 97 ± 2． 24‰, and 0. 97 ± 0. 74‰, respectively. The micronu cleus ratio of the patients' group was slgnificantly higher than that of the control group. It was suggested that the above patients had heritable base of disease genesis. The data provid ed in this papcr might be of value to the fundamental research of hyperthriodism genesis.