胃息肉与幽门螺杆菌(附111例胃息肉临床分析)

GASTRIC POLYPS AND HELICOBACTER PYLORICLINICAL STUDY OF 111 CASES

为了研究胃息肉与幽门螺杆菌(Helicobacter pylori,HP)感染的关系,对111例140枚经胃镜检查发现的胃息肉进行了分析。结果表明:炎症性息肉占75％,非炎症性息肉25％(包括息肉样变13枚),息肉样腺瘤17枚,管状和绒毛状腺瘤各2枚,息肉类癌1枚,息肉复发1枚)。发生在胃窦者占55％。直径大于2cm占2.8％,属于管状和绒毛状腺瘤。HP在胃息肉患者中总检出率50.7％,其中炎性息肉检出68.1％,非炎性息肉检出率16.7％,两者之间有显著性差异(P<0.05)。胃息肉伴慢性活动性炎者中HP检出率78.9％,非活动性炎仅18.2％,两者之间有显著性差异(P<0.005)。该研究还发现胃息肉发生随年龄增长而增加。研究表明HP在炎性息肉中有较高的检出率,而且大多伴有慢性活动性炎症,说明HP感染与炎症性息肉关系密切,可能是引起活动性炎症和炎症性胃息肉的重要原因之一。

To investigate the relationship between gastric polyps and H. Pylori infection, 111 patients with 140 gastric polyps identified by gastroscopy were studied. The results showed that 75% of the polyps were inflammatory polyps and the others were non-inflammatory polyps including 13 polyploid lesions. 17 polypoid adenoma, 2 tublar adeno- ma, 2 villous adenoma, 1 polypoid carcinoid and 1 polypus released after polypectomy. 55% of the polyps occurred in the antrum. 2.8% of the polyps had diameters greater than 2.0cm,and 58.6% of the polyps had diameters smaller than 0.5cm. H. pylori infection was found in 50.7% of all cases, in 68.1% of those with inflammatory polyps, and in 16.7% of those with non-inflammatory polyps. This difference is statistically significant (P<0.005). There was also a significant difference between the number of H. pylori infected cases with chronic active inflammation (78.9%), and those with inactive inflammation (18.2%) (P<0.005). In addition, the study looked at the increasing prevalence of gastric polyps with age. The research indicates that H. pylori infection may be one of the causes of active inflammatory polyps.