血必净注射液治疗慢性阻塞性肺疾病急性加重期的临床疗效观察

Efficacy of xuebijing injection in AECOPD

目的:探讨血必净注射液治疗慢性阻塞性肺疾病急性加重期的临床疗效。方法:将128例慢性阻塞性肺疾病急性加重期患者随机分为治疗组65例和对照组63例。对照组给予常规治疗;治疗组在此基础上加用血必净注射液50ml,静脉滴注,bid,疗程均为10 d。结果:治疗组有效率为96.92%,对照组为83.61%,P<0.05;平均住院日治疗组为(13.85±3.11)d,对照组为(16.09±4.89)d;治疗组在治疗期间有1例发生轻微不良反应。结论:血必净注射液配合常规治疗可提高慢性阻塞性肺疾病急性加重期疗效。

OBJECTIVE To investigate the effect of Xuebijing in AECOPD. METHODS 128 patients with AECOPD were randomly divided into two groups： 65 cases in xuebijing group and 63 cases in control group. Control group gave routine treatment, and xuebijing group added xuebijing injection 50 ml, iv drip, bid, for 10 d. RESULTS The effective rates were 96.92% and 83. 61% for the two groups （P 〈 0. 05 ） ; the average time in hospital was （13.85±3.11） d and （16.09±4.89） d （P 〈0.05）; One case ADR occurred in xuebijing group. CONCLUSION The efficacy of xuebijing in treating AECOPD was more satisfactory and safety.