我院住院患者抗菌药物应用情况调查分析

Analysis on Application of Antimicrobial Agents in Our Hospital

为了评价我院抗菌药物的合理应用情况。提取我院2006年1-10月住院患者药疗医嘱279307条,采用限定日剂量(DDD)的分析方法,并结合药物利用指数(DUI)对其中含抗菌药物的医嘱进行统计和分析。结果表明,抗菌药物医嘱条数占总医嘱数的44.30%,用药金额占总用药金额的48.57%;头孢菌素类药物用药金额居第一;在DDDs排序中口服类药物的总DDDs高于注射类,分别以美爱克片、可乐必妥片最高;大部分抗菌药物DUI接近1。说明我院抗菌药物应用基本合理,但用药比例过高,应采取积极有效的手段控制用药比例,防止抗菌药物滥用。

To estimate the rationality of the application of antimicrobial agents in our hospital,279 307 doctor＇s advice and prescriptions from January to October in 2006 were collected. The frequency and cost of antimicrobial were investigated and analyzed with DDD and DUI methods. In all the advices and prescriptions, 44.30% advices were about administration of antimicrobial. The consumption of antimicrobial accounted for 48.57% of the sum of money for total consumption of drugs, in which Cephalosporins occupied the first place in the sequence of consumption. The ratio of DDDs of oral preparation was higher than those of the injection ones. Cefditoren pivoxil tablets and Levofloxacin tablets were the top two drugs in all antimicrobial DDDs. The DUI of most of antimicrobial agents was close to 1. The conclusion is that our hospital＇ s application of antimicrobial agents is about reasonable, but the proportion of ones lies in the too highly level. Active and efficient ways are adopted to control this proportion and prevent from abusing antimicrobial agents.