危重病患儿内环境紊乱的临床研究

A clinical study on internal milieu disorder in children with critical ill

目的:探讨危重病患儿血糖及血清钠、钾、钙的变化及其相互关系。方法:对我院儿科2003年1月至2004年12月收治的46例危重病患儿进行血糖及血清钠、钾、钙的动态监测,并以46例轻症患儿为对照组进行比较。结果:危重病患儿容易发生应激性高血糖、低钠血症、低钾血症和低钙血症。应激性高血糖可加重内环境紊乱,使病情进一步恶化。结论:危重病患儿存在应激损伤,机体过度应激反应可引起血清电解质的改变,由此加重内环境紊乱,故控制过度应激反应,稳定内环境对危重病患儿极为重要。

Objective ：To explore the relationship and changes among blood glucose ,serum Na^＋ ,K^＋as well as blood calcium in critical ill children. Methods：We detected dynamic changes of 4 indexes in 46 hospitallized pediatric patients who suffered from critical ill. The detected items include blood glucose,serum Na^＋, K^＋ as well as blood calcium. Meanwhile a compartive analysis was done in 46 light ill children as controls. Results ：Children who involved in criti- cal ill constantly showed hyperglycemia,hyponatremia,hypocalcemia and hypokalemia. Irritable hyperglycemia could make the serum electrolyte out of balance more serious. Conclusion ：There really exist damage from stress in critical ill children. The severe stress could make the serum electrolyte out of balance more serious. It must be beneficial for these patients to control excessive stress.