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Smith抗原的性质特征及临床意义 被引量:1

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摘要 系统性红斑狼疮(systemic lupus erythematosus,SLE)是一种自身免疫性疾病,发病率有所上升,患者血清中可检出多种自身抗体,其中抗双链DNA(ds—DNA)抗体特异性和敏感性较高,而抗Sm抗体特异性高于抗ds—DNA抗体,被认为是SLE的标志性抗体,并已成为美国风湿病协会(ARA)1997年修订的诊断标准之一。本文就Sm抗原的理化特性、抗Sm抗体的检测和生物学作用作一综述。
出处 《福州总医院学报》 2007年第3期201-203,173,共4页 Journal of Fuzhou General Hospital
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