高血压病中医证型与血液流变学及胰岛素抵抗的相关性研究

The Research on the Relationship among TCM Syndrome Differentiation of Hypertension,Blood Rheology and Insulin Resistance

目的探讨高血压病患者血液流变学及胰岛素抵抗(IR)与人体内环境的内在联系。方法将符合入选标准的108例患者进行中医辨证分型,测定空腹血糖、空腹胰岛素和血液流变学指标,并以空腹血糖值及空腹胰岛素水平判断IR。结果患者中空腹血糖值、空腹胰岛素水平及血液流变学指标在各证型之间存在明显的差异性,其高低顺序为:痰湿壅盛型>肝阳上亢型>肝肾阴虚型>阴阳两虚型;表明高血压病辨证分型与血液流变学及IR之间存在明显的相关性。结论高血压病实证存在明显的IR和高粘滞血症,这种认识对中西医结合临床治疗及研究具有指导意义。

Objective： To discuss the internal relationship among the blood rheology of hypertension - suffering patients, insulin resistance （IR） and the interior body environment. Methods： 308 patients matching the standard are selected and differentiated TCM syndromes. The fasting blood - glucose, fasting insulin and blood rheology index are detected, and IR is evaluated by the fasting blood - glucose value and fasting insulin level. Results ： There exists significant difference between the patients＇fasting blood - glucose value, fasting insulin level and blood rheology index in different TCM syndromes, the sequence is- the type of the stagna- tion of phlegm - dampness 〉 the type of hyperactivity of liver - yang 〉 the type of deficiency of liver - yin and kidney - yin 〉 the type of deficiency of both yin and yang, which shows that there exists significant relation among the differentiation syndromes of hypertension, blood rheology and insulin resistance. Conclusions： There exists significant IR and hyperviscosity blood syndrome, which carries guiding significance in Integrated TCM and Western Medical treatment and research.