胎肾移植八例报告

Application of kidneys from fetal cadaver donors in adult renal transplantation

为扩大供肾来源，探索胎肾移植的临床特点，通过对8例股肾移植患者的观察，对手术特点、免疫抑制治疗方案和移植肾代偿的速度和类型等方面进行了研究。人／肾存活1年以上者4例，最长已达60个月，术后第5天24小时原量平均达1200ml，血肌酐在术后1～3个月降至正常水平。结果袁明，胎肾移植术后的管理与成人肾移植有一定差别，如胎肾得到良好保护，其功能和组织发育迅速。

In order to enlarge the source of kidneys for transplantation and to study the clinical application of embryonic kidneys in renal transplantation, 8 patients receiving embryonic kidneys were observed in terms of surgical procedures, regime of immunos uppre s s a nt therapy and the time and types of kidney compensation etc.. In 4 out 8 cases, the survival of patients and kidneys was over 1 year, the longest being 60 months. The urinary output 24 hours after transplantation was 1200ml on average and the serum creatine level dropped to normal 1~3 months after operation. Our results suggested that the management of patients with fetal cadaveric kidneys should be different from that with kidneys from adults, and the fetal grafts, if well protected, had better development of functions and tissues.