环形连续交锁缝合在新鲜羊膜移植术中的应用

Application of toroid continous interlocking suture in fresh amniotic membrane grafting

目的 探讨环形连续交锁缝合法在新鲜羊膜移植术中的应用及其临床效果.方法 选择本院行新鲜羊膜移植术的患者45例（52眼）,观察组23例（26眼）应用环形连续交锁缝合法,对照组22例（26眼）应用间断缝合法,随访3～6个月,比较2组羊膜植片及创面修复情况.结果 3周内羊膜自行脱落者,观察组3例,对照组11例,2组之间有显著性差异（P＜0.05）;羊膜完整保留3周以上者,观察组14例,对照组6例,2组之间有显著性差异（P＜0.05）;术后创面未修复者,观察组5例,对照组3例,2组之间无统计学意义（P＞0.05）.结论 环形连续交锁缝合法可使羊膜固定贴附于眼表创面,延长羊膜在眼表存留时间,刺激症状较轻,有利于眼表组织修复.

Objective To explore the application and clinical curative effects of toroid continous interlocking suture in fresh amniotic membrane grafting. Methods 45 patients who would be treated with fresh amniotic membrane grafting were divided into study group （ n = 23 ） with toroid continuous interloclong suture and control group（ n = 22） with interrupted suture. After following up for 3 -6 months,amnio - implants and restoration of raw surface were compared between the 2 groups. Results Within 3 weeks, patients whose amnion autotomy were 3 in the study group and 11 in the control group. There was significant difference between the two groups （ P 〈 0.05 ） ; after the operation,patients whose amnion complete remaining for more than 3 weeks were 14 in the study group and 6 in the control group, which showed statistically significant difference（ P 〈 0.05 ） ; after operation, patients whose raw surface not yet restored were 5 in the research group and 3 in the control group, which showed no statistical significance （ P 〉 0.05 ）. Conclusion Toroid eontinous interlocking suture can make amniou fixedly sticking to raw surface, extend persistenee time of amnion on eye,and its irritations are milder that are good for ocular - surface tissue restoration.