端粒酶系统在眼部疾病中的研究进展

Progress in study of telemerase system of ocular disease

端粒酶系统是端粒和端粒酶的总称。由于其与细胞衰老、增生乃至癌变的关系密切,端粒酶系统现已成为癌症及其他增生性疾病治疗研究的热点。大量研究表明,端粒酶的活性与眼部组织的增生、细胞的衰老及眼部肿瘤的发生关系密切。在此,我们就端粒、端粒酶研究现状及其与眼科疾病的关系和应用进展作一综述。

Telomerase system is the genetic name of telomerase and telomere. Because it relates intimately on the cells＇ aging and proliferation and the developing of neoplasm,telomerase system has become a hot point of treatment research. A lot of research has indicated that telomerase system has important effect upon eye in cells＇ aging and proliferation. We summarize the present research of telomerase and telomere and their applications on ocular disease.