放射性皮炎的防治研究现状

Prevention and treatment of acute radiodermatitis for patients receiving radiotherapy

放射性皮炎是肿瘤放射治疗最常见的并发症,其预防和治疗一直是放疗界关注的问题。放射性皮炎的评价目前主要基于医生的主观评价,一些客观评价方法用于临床实践还需要进一步的研究。许多因素影响放射性皮炎的发生及其严重程度,包括内在因素和外在因素。除常规的护理以外,药物是放射性皮炎防治很重要的手段,如植物提取物(包括芦荟凝胶和植物油类)、维生素类(包括维生素C、维生素B12和维生素E等)、乳膏类(激素类乳膏和比亚芬等)、重组人表皮生长因子和中药等。许多学者对以上药物的防治效果进行了研究,但评价不一,期待更为有效的防治措施和方法出现。

Radiodermatitis is one of the most familiar compli-cations in tumor radiotherapy which draws a great attention of both physicians and patients. Currently the evaluation of radiodermatitis mainly depends on the doctor＇s subjective observation. Some objec-tive evaluation methods still need further research. Many factors in fluence the occurrence and degree of the radiodermatitis which in-clude internal factors and external factors. Medicines are very im- portant means to prevent and treat radiodermitis. Such as, the plant extract including aloe gel, plantoil; the vitamins include vita- min C, vitamin B12 and vitamin E; the creams mainly including hor-mone creams and Biafine cream; reorganized epidermis growth fac-tor; Chinese herbal medicine, etc. The prevention and therapeatic effects of the above medicines were studied, but the results varied. More valid methods are expected to prevent and treat radiodermati-tis.