发酵法生产甲壳素纤维

Production of chitin fibers by fermentation

为了找到一种可以大规模生产甲壳素的方法,研究了利用丝状真菌生产甲壳素纤维的发酵工艺.结果显示犁头霉属真菌生产甲壳素的能力最高,每200 mL培养液中最多可提取200 mg甲壳素.丝状真菌发酵后得到的甲壳素为中空纤维状物质,其长度在50～100 mm,与纺织用纤维的长度基本相同.这种纤维经过处理后可以通过造纸工艺直接加工成类似于水刺非织造布的结构.研究结果证明采用发酵法制备的甲壳素纤维具有很好的生物活性,它们能吸附并结合细胞,加快细胞的繁殖,用做医用敷料可以有效地促进伤口的愈合.

In order to find out a mass production method of chitin, this paper studied the production process for chitin by using the fermentation of fungi. Results showed that Absidia fungi yields the highest volume of chitin, producing up to 200 mg chitin per 200 mL culture media. The chitin produced through the fermentation process takes the form of hollow fibers, with the length ranging from 50 to 100 mm, similar to that of textile fiber. After treatment, these fibers can be made into a structure similar to hydroentangled nonwoven by the paper making process. The research demonstrated that the chitin fiber made by fermentation has very good bioactivity, is bio-adsorbable, and facilitates the growth of cell and accelerates wound healing when used as medical dressings.