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妊娠相关蛋白-A与冠心病关系研究新进展 被引量：1

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摘要 妊娠相关蛋白-A是诊断冠心病的新标记物,不但能够早期诊断还可以危险分层、预测预后、指导治疗,现就其作用机制和临床意义作简要综述。
作者 吴凡 万征
机构地区 天津医科大学总医院
出处 《实用心脑肺血管病杂志》 2007年第7期556-560,共5页 Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
关键词 妊娠相关蛋白-A 冠心痛 急性冠脉综合征
分类号 R543.31 [医药卫生—心血管疾病]
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参考文献21

  • 1Bayes-Genis A,Conover CA,Overgaard MT,et al.Pregnancy-associated plasma protein A as a marker of acute coronary syndromes.N Engl J Med.2001,345:1022-9.
  • 2Ahmed A.Elesber,Cheryl A.Conover,Ali E.Denktas,et al:Prognostic value of circulating pregnancy-associated plasma protein levels in patients with chronic stable angina.European Heart Journal.2006.27:1678-84.
  • 3Wald NJ,George L,Smith D,et al.Serum screening for Down's syndrome between 8 and 14 weeks of pregnancy for the International Prenatal Screening Research Group.Br J Obsbet Gynaecol.1996.103:407-12.
  • 4Qin QP,Kokkala S,Lund J,et al.Immunoassays developed for pregnancy-associated plasma protein-A (PAPP-A)in pregnancy may not recognize PAPP-A in acute coronary syndromes.Clin Chem.2006,52(3):398-404.
  • 5Saara Wittfooth,Qiu-Ping Qin,Juha Land,et al.Harri Takalo and Kim Pettersson.Immunofluorometric Point-of-Care Assays for the Detection of Acute Coronary Syndrome-Related Noncomplexed Pregnancy-Associated Plasma Protein A.Clin Chem.2006,52(9):1794-801.
  • 6Conover CA,Bale LK,Harrington SC,et aL.Cytokine stimulation of pregnancy-associated plasma protein A expression in human coronary artery smooth muscle cells:inhibition by resveratrol.Am J Physiol Cell Physiol.2006,290(1):183-8.
  • 7李卫萍,顾复生,贾三庆.C反应蛋白和肿瘤坏死因子-α对单核细胞妊娠相关血浆蛋白-AmRNA表达影响的实验研究[J].中华心血管病杂志,2006,34(12):1117-1121. 被引量：12
  • 8Conover,Cheryl A.Harrington,Scan C.Bale,Laurie K.Oxvig,Claus.Surface association of pregnancy-associated plasma pmtein-A accounts for its colocalization with activated macrophnges.American Journal of Physiology Heart ＆ Circulatory Physiology.2007,292 (2):H994-H1000.
  • 9Claus Gyrup and Claus Oxvig.Quantitative Analysis of Insulin-like Growth Factor-Modulated Proteolysis of Insulin-like Growth Factor Binding Protein-4 and-5 by Pregnancy-Associated Plasma Protein-A.Biochemistry.2007,46(7):1972-80
  • 10Zachary T.Simari,Robert D.Conover,Cheryl A.Targeted Disruption of the Pregnancy-Associated Plasma Protein-A Gene Is Associated with Diminished Smooth Muscle Cell Response to Insulin-like Growth Factor-I and Resistance to Neointimal Hyperplasia after Vascular Injury.Endocrinology.2006,147(12):5634-40.

二级参考文献14

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  • 5Resch ZT,Chen BK,Bale LK,et al.Pregnancy-associated plasma protein a gene expression as a target of inflammatory cytokines.Endocrinology,2004,145:1124-1129.
  • 6Zwaka TP,Hombach V,Torzewski J.C-reactive protein-mediated low density lipoprotein uptake by macrophages:implications for atherosclerosis.Circulation,2001,103:1194-1197.
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实用心脑肺血管病杂志
2007年 第7期

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