气相色谱-质谱法测定包装材料中全氟辛酸及其盐类

Determination of perflurooctanoic acid and its salts in packaging materials using GC-MS

快速溶剂萃取法萃取包装材料中的全氟辛酸（PFOA）及其盐类,萃取液与乙酰化试剂反应后,以全氟癸酸甲酯为内标物,用内标法进行定量测定。气相色谱质谱条件为：HP-Innowax毛细柱;柱温：50℃（5 min）→30℃/min 240℃（5 min）;不分流进样;接口温度：280℃;载气：氦气,0.8 mL/min;进样量：1μL;负化学源;反应气：甲烷,20%;选择离子扫描方式。方法的线性范围1.0-105μg/L,线性相关系数r=0.999,检出限0.1μg/L,不同浓度的PFOA的相对标准偏差分别为4.1%和3.2%,回收率在87%-109%之间。

Accelerated solvent extraction （ASE） technique was used to extract perflurooctanoic acid （PFOA） and its salts from packaging materials. The extract was quantified after reacting with acetyl reagent by gas chromatographymass spectrometric （GC-MS） method using perflurodecanoic acid methyl ester as an internal standard. The GC - MS conditions were： HP-Innowax capillary column; oven temperature, 50 ℃ （5 min）→30℃/min 240 ℃ （5 min）; splittless mode; injection volume, 1 μL; chemical ion source, reacting gas, CH4, 20% ; selective ion scan mode （SIM） ; Linear range was 1.0 - 10^5 μg/L; the correlation coefficient was 0.999; the lowest limit of detection was 0.1μg/L. The RSD was 3.2 % and 4.1% respectively for low and high concentration of PFOA, and the recoveries were between 87% - 109%.