肝硬化患者血清INS与HA、PⅢP水平的相关性分析

Study on the Relationship Between Serum Levels of INS and HA,PⅢP in Patients with Liver Cirrhosis

目的:探讨了肝硬化患者血清胰岛素(INS)水平及其与血清透明质酸(HA)、胶原蛋白Ⅲ(PⅢP)的关系。方法:应用放射免疫分析测定了68例肝硬化患者血清INS和HA、PⅢP含量,并与35名正常人作比较。结果:肝硬化患者血清INS、HA和PⅢP水平均非常显著地高于正常人组(P<0.01)且血清INS水平与HA、PⅢP水平呈明显的正相关(r=0.7125、0.8133,P<0.01)。结论:检测肝硬化患者血清INS和HA、PⅢP水平的变化对疾病的诊断、治疗是一个有用的检测指标。

Objective To explore the clinical significance of changes of serum INS and HA, P lit P levels in patients with liver cirrhosis. Methods Serum INS, HA and PⅢP levels were measured with IdA in 68 patients with liver eirrhosis as well as 35 controls. Results The levels of serum INS, HA and P lit P were significantly higher in the patients than those in controls （ P 〈 0.01 ）, serum INS and HA ,PⅢP levels weremutually positively correlated（r=0.7125,0.8133,P〈0.01）. Conclusion Detection of serurn INS, HA, PⅢP levels might be of diagnostic and prognostic values in patients with liver cirrhosis.