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Controversies in and challenges to our understanding of hepatitis C

Controversies in and challenges to our understanding of hepatitis C
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摘要 Discovered in 1989, the hepatitis C virus (HCV) continues to cause signifi cant morbidity and mortality world-wide despite a huge research commitment to defining and understanding the virus and the disease it causes. This paper discusses a number of areas where progress in the management of the HCV have not kept pace with the scientifi c understanding of the HCV. It is suggested that in the fi elds of HCV prevention and providing access to treatment, practice falls short of what could be achieved. The role of alcohol in the pathogenesis of HCV liver injury is discussed. Discrimination against those with HCV infection and particularly those in prison settings fails to match good clinical practice. The complicated processes of sharing information between specialty groups is also discussed in an attempt to optimise knowledge dissemination in this field. Discovered in 1989, the hepatitis C virus (HCV) continues to cause significant morbidity and mortality world-wide despite a huge research commitment to defining and understanding the virus and the disease it causes. This paper discusses a number of areas where progress in the management of the HCV have not kept pace with the scientific understanding of the HCV. It is suggested that in the fields of HCV prevention and providing access to treatment, practice falls short of what could be achieved. The role of alcohol in the pathogenesis of HCV liver injury is discussed. Discrimination against those with HCV infection and particularly those in prison settings fails to match good clinical practice. The complicated processes of sharing information between specialty groups is also discussed in an attempt to optimise knowledge dissemination in this field.
机构地区 Area Director
出处 《World Journal of Gastroenterology》 SCIE CAS CSCD 2007年第31期4168-4176,共9页 世界胃肠病学杂志(英文版)
关键词 Hepatitis C ALCOHOL Injecting drug use Prisons Genetic variation CIRRHOSIS Liver cell cancer 丙型病毒肝炎 酒精依赖 药物注射 肝硬化
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  • 1[1]Conry-Cantilena C,VanRaden M,Gibble J,Melpolder J,Shakil AO,Viladomiu L,Cheung L,DiBisceglie A,Hoofnagle J,Shih JW,Kaslow R,Ness P,Alter HJ.Routes of infection,viremia,and liver disease in blood donors found to have hepatitis C virus infection.N Engl J Med 1996; 334:1691-1696
  • 2[2]Alter MJ,Margolis HS,Krawczynski K,Judson FN,Mares A,Alexander WJ,Hu PY,Miller JK,Gerber MA,Sampliner RE.The natural history of community-acquired hepatitis C in the United States.The Sentinel Counties Chronic non-A,non-B Hepatitis Study Team.N Engl J Med 1992; 327:1899-1905
  • 3[3]Alter HJ,Conry-Cantilena C,Melpolder J,Tan D,Van Raden M,Herion D,Lau D,Hoofnagle JH.Hepatitis C in asymptomatic blood donors.Hepatology 1997; 26(Suppl 1):29-33
  • 4[4]Crofts N,Hopper JL,Milner R,Breschkin AM,Bowden DS,Locarnini SA.Blood-borne virus infections among Australian injecting drug users:implications for spread of HIV.Eur J Epidemiol 1994; 10:687-694
  • 5[5]Goldberg D,Cameron S,McMenamin J.Hepatitis C virus antibody prevalence among injecting drug users in Glasgow has fallen but remains high.Commun Dis Public Health 1998;1:95-97
  • 6[6]Samuel MC,Doherty PM,Bulterys M,Jenison SA.Association between heroin use,needle sharing and tattoos received in prison with hepatitis B and C positivity among streetrecruited injecting drug users in New Mexico,USA.Epidemiol Infect 2001; 127:475-484
  • 7[7]Alter MJ.Hepatitis C virus infection in the United States.J Hepatol 1999; 31:88-91
  • 8[8]Alavian SM,Gholami B,Masarrat S.Hepatitis C risk factors in Iranian volunteer blood donors:a case-control study.J Gastroenterol Hepatol 2002; 17:1092-1097
  • 9[9]Zali MR,Noroozi A,Amirrasooli H,Darvishi M.Prevalence of Anti-HCV antibody and routes of hematological transmission in addicts of Ghasr prison[in persian].Pajouhesh 1998;22:26-32
  • 10[10]Skipper C,Guy JM,Parkes J,Roderick P,Rosenberg WM.Evaluation of a prison outreach clinic for the diagnosis and prevention of hepatitis C:implications for the national strategy.Gut 2003; 52:1500-1504

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