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基于EB病毒的肿瘤靶向治疗策略 被引量：1

Virally targeted therapies for EBV-associated neoplasms
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摘要 爱泼斯坦-巴尔病毒（EBV）相关肿瘤中存在EBV及其产物，为特异性杀伤肿瘤细胞提供了理想靶点。通过抑制EBV转化蛋白表达，靶向EBV复制启动元件，诱导EBV裂解感染以及EBV特异性免疫治疗等途径，为肿瘤治疗提供了新的以病毒为靶点的治疗策略。 The presence of the EBV genome within related tumors presents us with ideal target for cancer treatments. EBV-targeted strategies for treating cancer include inhibiting EBV transforming proteins, targeting Orip replication complexes, induction of the lytic form of EBV infection, and EBV specific immunotherapy. In this article, we will review a variety of different virally targeted therapies for EBV-associated neoplasms.
作者 景钊 张薛榜 吴式跨（综述）
机构地区 温州医学院附属第一医院放疗科
出处 《国际肿瘤学杂志》 CAS 2007年第7期481-483,共3页 Journal of International Oncology
基金 国家自然科学基金资助项目（30670621）
关键词 疱疹病毒4型 人 免疫疗法 肿瘤 Herpesvirus 4, human Immunotherapy Neoplasms
分类号 R730 [医药卫生—肿瘤]
  • 相关文献

参考文献18

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共引文献1

同被引文献14

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二级引证文献29

国际肿瘤学杂志
2007年 第7期

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