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髓系/NK细胞急性白血病一例 被引量:2

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摘要 患者男,43岁。因“乏力、四肢皮肤淤点、淤斑3个月”于2005年9月7日收入我科。患者于3个月前无诱因出现乏力、皮肤淤点、淤斑,反复发作。入院体检:皮肤可见散在淤点、淤斑,浅表淋巴结未及,胸骨压痛阳性,肝、脾肋下均4cm;血象Hb114g/L,WBC59.8×10^9/L,PLT 9×10^9/L。骨髓象增生极度活跃,异常早幼粒细胞占0.82,该类细胞胞体大小不等,可见伪足,浆量多,浆内可见大量细小的紫红色颗粒,
出处 《中华内科杂志》 CAS CSCD 北大核心 2007年第8期636-636,共1页 Chinese Journal of Internal Medicine
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  • 1仇惠英,薛永权,潘金兰,吴亚芳,张俊,马勤芬,岑建农.一例伴有t(4;12)(q11;q13)的急性髓系/NK细胞白血病的临床和实验研究[J].中华血液学杂志,2007,28(7):489-491. 被引量:2
  • 2I_o-Coco F,Ammatuna E, Montesinos P,et al. Acute promyelocytic leukemia: recent advances in diagnosis and management. Semi On- col,2008 ;35(4) :401 -409.
  • 3Scott AA, Head DR, Kopecky KJ, et al. HLA-DR- , CD33 ^+, CD56^+ , CD16^- myeloid/natural killer cell acute leukemia: A previ- ously unrecognized form of acute leukemia potentially misdiagnosed as French-American-British acute myeloid leukemia-M3. Blood, 1994; 84( 1 ) :244 - 256.
  • 4Rubio-Batll6s M, de la Mata AC, Macias JRR, et al. Isolated a- symptomatic severe neutropenia as the presentation of myeloid/natu- ral killer cell acute leukemia. Haematologiea, 2000 ; 85 ( 3 ) : 322 - 323.
  • 5Burgaleta C, de Mignel D, Rubio ML, et al. Myeloid natural killer cell leukemia resembling a variant of acute promyelocytie leukemia. Haematologica, 2001 ; 86 ( 7 ) : 765 - 766.
  • 6Sun T, Pashaei S, Jaffrey I, et al. A hybrid form of myeloid/NK-cell acute leukemia and myeloid/NK-eell precursor acute leukemia. Hu- man Pathol,2003 ;34(5) :504-508.
  • 7Tang G,Truong F, Fadare O, et al. Diagnostic challenges related to myeloid/natural killer cells, a variant of myeloblasts. Int J Clin Exp Patho1,2008 ; 1 (6) :544 - 549.
  • 8Chen B,Xu X,Ji M,et al. Myeloid/NK cell acute leukemia. Int J Hemato1,2009 ;89 ( 3 ) :365 - 367.
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  • 10Oshimi K. Progress in understanding and managing natural kill-cell malignancies. Br J Haematol,2007 ; 139 (4) :532 - 544.

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