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早产儿视网膜病变致病相关基因多态性研究现状 被引量：1

Studies of genetic polymorphism in retinopathy of prematurity
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摘要 早产儿视网膜病变是一种发生于短孕周、低出生体重早产儿的视网膜血管增生性疾病。不同国家、不同种族中，早产儿视网膜病变的发病率不同，相同干预措施下疾病的转归也不同。由此表明早产儿视网膜病变可能与遗传因素有关。目前认为有数种基因在早产儿视网膜病变中起作用，因此有必要就早产儿视网膜病变的相关致病基因研究现状进行综述。 Retinopathy of prematurity （ROP） is a vasoproliferative disease that happened in preterm infants with low gestational age and birth weight. Recently, many studies suggested that the incidence of ROP and the results of same clinical intervention vary between different races and countries. It seems that ROP may relate with genetic factors. Several genes are suggested to play a possible role in the occurrence of ROP. This paper reviews these related genes.
作者 李炜炜 郑穗联 施明光
机构地区 温州医学院附属第二医院眼科
出处 《中华眼科杂志》 CAS CSCD 北大核心 2007年第8期765-768,共4页 Chinese Journal of Ophthalmology
基金 温州市科委基金资助项目（S2002A038）
关键词 视网膜病 早产儿 多态现象(遗传学) Retinopathy of prematurity Polymorphism（genetics）
分类号 R686 [医药卫生—骨科学]
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参考文献34

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二级参考文献14

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中华眼科杂志
2007年 第8期

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