摘要
二膦酸盐具有很强的抗骨质吸收的作用,20世纪70年代开始应用于临床,已被证实对于良、恶性骨病有效,包括骨质疏松症、Paget病,一些代谢性骨病以及因乳腺癌、肺癌、前列腺癌所致骨转移及多发性骨髓瘤。二膦酸盐的作用主要是抑制破骨细胞,引起破骨细胞的凋亡。用于癌症患者可以防止骨骼并发症,减少骨痛,并且提高生存质量。
出处
《中华口腔医学杂志》
CAS
CSCD
北大核心
2007年第8期510-512,共3页
Chinese Journal of Stomatology
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