胎儿胃泡超声形态学表现与先天性消化道异常相关性研究

Study on the relativity between ultrasonic morphology of fetal stomach bubble and digestive tract abnormalities

目的:探讨胎儿胃泡超声形态学改变与先天性消化道异常的相关性。方法:对高度怀疑消化道异常胎儿,应用彩色多普勒超声分析胎儿胃泡超声形态学表现,并与分娩后新生儿科检查或胎儿尸体解剖检查结果进行对照,分析其与不同类型消化道异常的相关性。结果:胎儿胃泡超声形态学改变中,胃泡移位、幽门窦部蠕动浅缓与先天性隔疝呈正相关(P<0.01)。胃泡长、宽径增加及节律性幽门管显示与先天性肥厚性幽门狭窄呈正相关(P<0.05)。幽门扩张与十二指肠闭锁、空回肠闭锁呈正相关(P<0.01)。胎儿胃泡形态学改变与先天性直肠肛门闭锁无显著相关性(P>0.05)。结论:胎儿胃泡形态学改变,在消化道异常中具有一定的特征性,可作为诊断的重要指标。

Objective： Probe into the relativity between the ultrasonic morphology of fetal stomach bubble and digestive tract abnormalities. Methods： For the fetus who were highly suspicious of digestive tract abnormalities, color Doppler ultrasonic was applied to analyze the exhibitions of ultrasonic morphology of fetal stomach bubble to compare with the examination on the newborns after delivery or the fetal corpse in order to find out its relativity to the different types of digestive tract abnormality. Results： In the morphological changes of fetal stomach bubble, the movement of stomach bubble and the peristalsis of pyloric antrum were in positive relativity with congenital diaphragmatic hernia （P 〈 0. 01 ）. The increasing length and width of stomach bubble, as well as the rhythmicity of pylorus canal, were also in positive relativity with congenital hypertrophic pyloric stenosis （ P 〈 0. 05 ）. It was also true in the relation between the pylorus dilatation, duodenal atresia, jejunal and ileal atresia （ P 〈 0. 01 ）. However, the morphological changes of fetal stomach bubble had nothing to do with cogential anal atresia （ P 〉 0. 05 ） . Conclusion ： The morphological changes of fetal stomach bubble have certain features in digestive tract abnormalities, so it can be considered as an important indicator in diagnosis.