十一碳二元腈的合成

SYNTHESIS OF UNDECANONITRILE

以十一碳二元酸和氨气为原料合成了十一碳二元腈，考察了反应温度和时间对产物收率的影响。结果表明，不使用催化剂时，在反应温度300-350℃、反应时间7h条件下，产物收率为98．4％；使用磷酸作催化剂，反应时间2．5h、m（磷酸）：m（十一碳二元酸）=0．02：1时，产物收率达99．1％。产物经IR、^1H NMR进行了确认。

Undecanonitrile was synthesized from undecanedioic acid and ammonia. The key factors of the reaction were investigated. The optimal conditions obtained were showed as follows, reaction temperature 300- 350 ℃ and react With phosphoric acid been used 1, the yield could up to 99.1% time 7 h. Under these conditions the yield could reach 98. 4% as catalyst and re（phosphoric acid） ： m（undecanedioic acid） =0.02 within 2.5 h. Undecanonitrile was determined by IR and ^1H NMR.