摘要
目的:探讨肺炎衣原体(TWAR)与急性心梗(AMI)、心绞痛(Angina)型冠心病之间的关系。方法:采用多聚合酶链反应(PCR)技术对200例冠心病(急性心梗56例,不稳定心绞痛124例,稳定心绞痛20例)和180例非冠心病患者进行全血标本肺炎衣原体DNA检测。结果:急性心梗组肺炎衣原体DNA阳性率为73.2%,不稳定心绞痛组为52.4%,稳定心绞痛组为45.0%;对照组为21.1%,三组与对照组相比,差异均有显著性(P<0.01,P<0.01,P<0.05)。结论:肺炎衣原体感染与急性心梗、心绞痛型冠心病存在密切关系。
Objective: To investigate the relationship between chlamydia pneumoniae(TWAR) and coronary heart disease (CHD) with acute myocardio infarction or angina. Methods: By means of polymerase chain reaction(PCR) ,TWAR nucleic acid was detected in 56 patients with acute myocardio infarction, 124 patients with unstable angina,stable angina;and 180 control subjects. Results: The positive rates of TWAR-DNA were 73.2%,52.4%,45.0% in the AMI,unstable angina,stable angina patients and 21.1% in the control group respectively;which showed significant difference (P〈0. 01 ,P〈0.01,P〈0.05). Conclusion: TWAR infection is closely connected with CHD (acute myocardio infarction or angina) ,and may be one of the risk factors in CHD mechanisms.
出处
《河北北方学院学报(医学版)》
2007年第4期11-13,共3页
Journal of Hebei North University:Medical Edition
基金
河北省科学技术研究与发展指导计划项目(编号:002761107)
关键词
肺炎衣原体
急性心梗
心绞痛
多聚酶链反应
核酸
Chlamydia pneumoniae
Acute myocardio infarctions Angina
Polymerase chain reactions Nucleic acid