慈溪市肺癌危险因素病例对照研究

A Case-control Study on Risk Factors of Lung Cancer in Cixi City

目的探讨慈溪市居民肺癌的各种危险因素,为预防决策提供依据。方法采用1∶1频数匹配的病例对照研究,随机选择该市肺癌现症病例173人和对照人群173人,进行肺癌流行病学调查,并以条件Logistic回归分析各因素与肺癌发生的关系。结果体重指数(0.34)、吃新鲜青鲇鱼(0.35)是肺癌保护因素,而腰臀比(2.94)、吃动物内脏(4.05)、食糖摄入高(1.41)、吸烟(3.50)、家庭问题(1.82)、容易生气(3.18)、情绪自我调节能力差(9.01)和曾患肺部其他疾患(哮喘)(3.8)是肺癌的危险因素。结论目前影响慈溪市肺癌的主要因素为腰臀比、吃动物内脏、食糖摄入高、吸烟、家庭问题、容易生气、情绪自我调节能力差、曾患肺部其他疾患等。

Objective To provide evidence for decision-making on lung cancer prevention through studying the risk factors related to the incidence of lung cancer in Chinese people. Methods A frequency-matched design of case-control study was performed. 173 lung cancer patients and 173 matched controls were randomly selected from the residents of Cixi city. The relationship between lung cancer and risk factors was estimated using nonconditional logistic regression models. Results We observed reduced risk for lung cancer among people with BMI≥21 kg/m^3 （0.34） and taking fresh fish （0.35）. Some risk factors were found such as WHR （2.94）, unhealthly diet hobby （4.05）, high intake of sugar （1.41）, smoking （3.50）, often worrying about family problems （1.82）, depression （3.18）, poor ability in self-regulated mood （9.01） and personal history of respiratory system diseases （3.8）. Conclusion The main factors influencing the incidence of lung cancer in Cixi people were WHR, tmhealthly diet hobby, high intake of sugar, smoking, often worrying about family problems, depression, poor ability in self-regulated mood and personal history of respiratory system diseases.