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RNAi抑制胰腺癌细胞株VEGF表达的实验研究 被引量：2

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作者 赵鑫 李德春 张子祥 赵华 岑建农
机构地区 江苏省苏州大学附属第一医院普外科 江苏省血液研究所
出处 《肿瘤防治研究》 CAS CSCD 北大核心 2007年第8期636-638,共3页 Cancer Research on Prevention and Treatment
基金 卫生部科学研究基金资助项目(WKJ2004-2-011)
关键词 RNA干扰 PANC-1 VEGF PCR ELISA
分类号 R735.9 [医药卫生—肿瘤]
  • 相关文献

参考文献11

  • 1Kamat BR, Brown LF, Manseau EJ, et al. Expression of vascular permeability factor vascular endothelial growth factor by human granulose and the calutein cells[J]. Am J Pathol, 1995,146(1 ) : 157-165.
  • 2Dvorak HF, Brown LF, Detmar M, et al. Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis[J]. Am J Pathol, 1995, 146(5) : 1029-1039.
  • 3Fire A, Xu S, Montgomery MK, et al. Potent and specific genetic interference by double stranded RNA in Caenorhabditis elegans[J].Nature, 1998, 391 (6669) :806-811.
  • 4萨姆布鲁克J 拉塞尔DW 黄培堂 译.分子克隆实验指南[M](第3版)[M].北京:科学出版社,2002.463-465.
  • 5Brekken RA, Overholser JP, Stastny VA, et al. Selective inhibition of vascular endothelial growth factor(VEGF)receptor 2 (KDR/FIk-1) activity by a monoclonal anti-VEGF antibody blocks tumor growth in mice [J]. Cancer Res, 2000, 60 (18):5117-5124.
  • 6Im SA, Kin JS, Gomez Manzano C, et al. Inhibition of breast cancer growth in vivo by antiangiogenesis gene therapy with adenovirus-mediated antisense-VEGF [J]. Br J Cancer, 2001, 84(9) : 1252-1257.
  • 7Fraser A. RNA interference: human genes hit the big screen[J]. Nature, 2004,428 (6981 ) : 375-378.
  • 8Matsumoto G, Kushibiki T, Kinoshita Y,et al. Cationized gelatin delivery of a plasmid DNA expressing small interference RNA for VEGF inhibits murine squamous cell carcinoma [J].Cancer Sci, 2006, 97(4):313-321.
  • 9Miyagishi M, Taira K. U6 promoter-driven siRNAs with four uridine 3' overhangs efficiently suppress targeted gene expression in mammalian cells[J].Nature Biotech, 2002, 20 (5) : 497-500.
  • 10Niola F, Evangelisti C, Campagnolo L, et al. A plasmid-encoded VEGF siRNA reduces glioblastoma angiogenesis and its combination with interleukin-4 blocks tumor growth in a xenograft mouse model [J]. Cancer Biol Ther, 2006, 5 (2): 174- 179.

共引文献54

同被引文献9

  • 1Yoshiji H, Kuriyama S, Hicklin DJ, et al. KDR/Flk-1 is a major regulator of vascular endothelial growth factor-induced tumor development and angiogenesis in nmrine hepatocellular carcinoma cells [ J ]. Hepatology, 1999, 30(5): 1179-1186.
  • 2Wang S, Liu H, Ren L, et al. Inhibiting colorectal carcinoma growth and metastasis by expression of VEGF using RNA interference [ J ]. Neoplasia, 2008, 10(4) : 399 -407.
  • 3Maehara Y, Kakeji Y, Oda S, et al. Tumor growth patterns and biological characteristics of early gastric carcinoma[J]. Ontology, 2001, 61(2) : 102 -112.
  • 4Gruuewald M, Avraham I, Dor Y, et al. VEGF-induced adult neovascularization : recruitment, retention, and role of accessory cells [ J ]. Cell, 2006, 124(1) : 175 -189.
  • 5Couhas L, Chawengsaksophak K, Rossant J. Endothelial cells and VEGF in vascular development[J]. Nature, 2005, 438(7070) : 937 -945.
  • 6Cardones AR, Banez LL. VEGF inhibitors in cancer therapy[ J ]. Curr Pharm Des, 2006, 12(3) : 387 -394.
  • 7Donovan EA, Kummar S. Targeting VEGF in cancer therapy [J]. Curr Probl Cancer, 2006, 30 ( 1 ) : 7 - 32.
  • 8路武豪,娄卫华,赵国强.RNAi沉默喉鳞癌Hep-2细胞株VEGF-C mRNA基因表达的实验研究[J].肿瘤基础与临床,2008,21(2):99-102. 被引量：3
  • 9王崇强,范钰,徐永中,庞利群.RNAi沉默VEGF表达对大肠癌细胞肝转移的影响[J].江苏大学学报（医学版）,2008,18(4):291-294. 被引量：1

引证文献2

二级引证文献11

肿瘤防治研究
2007年 第8期

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