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高血压早期肾损害相关因素分析及其与颈动脉IMT的关系 被引量:1

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摘要 检测100例高血压患者血压、血生化指标及尿微量白蛋白(mAlb)、β2-微球蛋白(β2-MG)阳性率,分析尿mAlb、β2-MG显著相关性因素;比较尿白蛋白正常组(NAU组)和微量白蛋白尿组(MAU组),颈动脉内—中膜厚度(IMT)及硬化斑块指数(PI)。发现高血压患者尿mAlb、β2-MG阳性率较正常对照组明显升高(P<0.05),二者间有显著相关性(P<0.01)。高血压患者尿mAlb与颈动脉IMT呈正相关(P<0.01),MAU组、NAU组颈动脉IMT均较正常对照组明显增加(P均<0.05)。提示尿mAlb、β2-MG增高可以作为高血压早期肾损害敏感性指标,且尿mAlb与颈动脉IMT密切相关。
出处 《山东医药》 CAS 北大核心 2007年第19期106-107,共2页 Shandong Medical Journal
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