中西医结合治疗围绝经期综合征患者临床疗效观察

Clinical study on treatment of the patients with perimenopausal syndrome with the conbined treatment of traditional Chinese medicine and Western medicine

目的:研究中西医结合治疗围绝经期综合征患者前后甲襞微循环、雌激素及血脂变化。方法:对60例正常妇女(CON)、60例无症状围绝经期妇女(PM)、60例围绝经期综合征妇女(PMS)在治疗前检测甲襞微循环、雌激素及血脂,并进行组间比较;另外对PMS妇女在中西结合治疗后进行甲襞微循环、雌激素及血脂检测,并与治疗前对比观察。结果:PM组和PMS组分别与CON组甲襞微循环、雌激素及血脂比较,差异有非常显著性(P<0.01);PM组和PMS组甲襞微循环、雌激素及血脂比较,无统计学意义(P>0.05);PMS组中西药结合治疗前后甲襞微循环、雌激素及血脂比较,差异有非常显著性(P<0.01)。结论:中西医结合治疗围绝经期综合征,可使甲襞微循环、雌激素及血脂指标有显著的改善,疗效肯定。

Objective：To explore the change of nail fold microcirculation,female hormone and blood lipid on the patients with perimenopause syndrome before and after the conbined treatment of traditional Chinese medicine and Western medicine.Methods：The several data of nail fold microcirculation,female hormone and blood lipid were obtained and compared among three groups before treatment. The three groups were Group Control,Group PM （women in perimenopausal period） and Group PMS（patients with perimenopausal syndrome）,60 samples in each group.And the above data were compared in Group PMS before and after treatment. Results：There was significant difference of nail fold microcirculation,female hormone and blood lipid among Group Control,Group PM and Group PMS before treatment of traditional Chinese medicine and Western medicine （P〈0.01）.And the difference of those between Group PM and Group PMS was not significant（P〉0.05）,but was significant in Group PMS before and after treatment （P〈0.01）.Conclusion：The conbined treatment of traditional Chinese medicine and Western medicine could improve nail fold microcirculation, female hormone and blood lipid.