摘要
目的评价高龄冠心病人长期服用曲美他嗪治疗心绞痛的疗效和耐受性。方法观察72例冠心病心绞痛病人,分为常规治疗对照组35例,治疗组37例常规治疗加服曲美他嗪。观察两组病人治疗前后心绞痛的发作次数及程度,以及肝肾功能、血脂、心率的变化和有无副反应。结果治疗组治疗后心绞痛减少明显(P<0.01),运动耐量增加(P<0.05),但两组治疗后心绞痛减少的对比无显著差异。心电图异常均有不同程度的改善,无明显不良反应。结论高龄冠心病人长期服用曲美他嗪治疗心绞痛是安全有效的。
Objective To observe the clinical effects of tremetazidine on venerable age patients of angina pectoris of coronary heart disease. Methods Seventy two patients were divided into conventional treatment group （ 35 cases ） and tremetazidine group （ 37 cases, treated with additional tremetazldine） . Break out times, degree of angina peetoris, change of liver function and kidney function, lipls, rates of heart beats, and side effect were recorded before and after the treatment for the two groups cases. Results After treatment, angina peetoris had reduced clearly in tremetazidine group（ P 〈0.01 ） ,and movement-endurance had increased （ P 〈0.05）. The improvement was shown on the electrocadigraphy for both groups . No adverse reaction was related to the tremetazidine group. Conclusion Tremetazidine is safe and effective to treat angina pecteris for venerable age patients of corenary heart disease in the long term.
出处
《内科》
2007年第4期493-494,共2页
Internal Medicine
