中国成年男子器官、组织和全身元素负荷量研究

Elemental burdens in organs or tissues and whole body for Chinese adult men

目的估算60种元素在中国成年男子主要器官、组织和全身的负荷量代表值。方法依据中国4个不同膳食类型地区采集68例急死正常成年男子尸体18种器官组织样品所测60种元素浓度代表值，按中国参考人器官、组织重量参考值估算了相应器官、组织和全身负荷量。结果补充或更新了中国成年男子60种元素在18种主要器官、组织和全身负荷量代表值。结论补充或更新结果为确定中国参考人器官、组织和全身这些元素负荷量参数参考值和背景值及计算元素某些生物动力学模型参数提供了较过去更全面和有代表性的依据。

Objective To estimate the representative burdens of the 60 elements in main organs or tissues and whole body for Chinese adult men. Methods The burdens in these organ or tissues and whole body were estimated by using relevant reference values of organ or tissue weights for Chinese Reference Man, based on the representative concentrations of 60 elements in the 18 kinds of organs or tissue samples, collected from autopsy of 68 subjects, who died suddenly, healthy and normal before death and hved in 4 areas with different dietary types in China. Results The representative burden data of the 60 elements in these organs or tissues and whole body for these Chinese adult men were supplemented or updated. Conclusions The supplemented or updated results obtained from this research have provided more comprehensive and representative basis for developing reference values of related elemental burden parameters in organs or tissues as well as whole body for Chinese Reference Man, background values of these elemental burdens and calculating some parameters of biokinetic model than before.