涎腺粘液表皮样癌术后生存的临床病理因素分析

Study on the Chinicopathologic Factors after Operation for the Survival of Mucoepidermoid Carcinoma in Salivary Glands

目的:探讨影响涎腺粘液表皮样癌患者术后生存的相关病理因素。方法:对98例涎腺粘液表皮样癌患者进行回顾性研究,分析影响患者术后生存的相关临床病理因素。通过SPSS10.0软件分析,筛选出影响粘液表皮样癌患者术后生存的主要临床病理因素。结果:与术后生存率相关的主要临床病理因素包括:临床分期、患者年龄、镜下是否发现坏死。结论:临床分期、患者年龄是影响涎腺粘液表皮样癌术后生存的主要临床因素,镜下坏死是影响涎腺粘液表皮样癌患者术后生存的主要病理因素。

Objective： To investigate the clinicopathological features of mucoepidermoid carcinoma in salivary gland in order to invprove diagnostic accuracy. The paraffin slides and clinical documents of 98 cases with mucoepidermoid carcinomas in Sslivary glangs were reviewed, and the correlative clinicopathologic factors influencing the survival were analyzed and the results were expected to be belpful for clinical practice. Methods： The logistic regression model was used to determine the main effective factors. Statistical analysis was performed using the SPSS10. 0 software. Results： The clinicopathologic factors correlated with decreasing in survial rates were： advanced clinical stage,older page（≥60）,necrotic presentation and metastatic presentation after operation. Conclusion： The important clinicopathologic factors including clinical stage, patient age and necrosis influence the survival rate of the patients with MEC in Salivary glands.