内镜下黏膜切除术治疗食管早期癌及癌前病变

Endoscopic mucosal resection for precancerous lesions and early esophageal cancer

目的:探讨内镜下黏膜切除术(EMR)治疗早期食管癌、癌前期病变的方法、效果及并发症。方法:2003年8月～2006年3月经色素内镜筛查且活检证实为早期癌及重度不典型增生41例患者,在异丙酚静脉麻醉下进行了EMR治疗,其中早期癌10例,重度不典型增生31例。结果:对早期癌及重度不典型增生的41例病人进行了内镜下EMR。出血、黏膜下血肿等并发症3例,无穿孔及狭窄等严重并发症。结论:EMR是治疗早期食管癌、癌前期病变的安全而有效的方法。

Objective：To explore the methods,effectiveness and complications of endoscopic mucosal resection（EMR） in the treatment of precancerous lesions and early esophageal cancer.Methods：From Aug 2003 to Mar 2006,EMR was performed on 41 patients with precancerous lesions and early esophageal cancer who were confirmed by chromoendoscopy with propofol phlebonarcosis ,which included 10 cases of early esophageal cancer, 31 cases of severe precancerous lesions.Results：EMR was performed on 41 patients with severe precancerous lesions and early esophageal cancer.There were 3 cases of complications which included asymptomatic bleeding,submuscosal haematoma,etc. Neither perforation nor stricture had occurred in these patients. Conclusion ：EMR is a promising clinical therapeutic masure showing the advantages of safety and effectiveness in the treatment of precancerous lesions and early esophageal cancer.