胼胝体发育不全并颅内畸形的MRI诊断

MRI Diagnosis of Dysgenesis of the Corpus Callosum Incorporate Encephalic Malformation

目的探讨胼胝体发育不全并颅内畸形的MRI诊断价值。资料与方法分析18例胼胝体发育不全并颅内畸形的常规MRI颅脑平扫资料。结果MRI显示10例胼胝体完全缺如,6例部分缺如,2例变薄。胼胝体发育不全在MRI上表现为半球间裂增宽,与第三脑室前部异常靠近或相连(100%);两侧脑室前角平直、分离;室间孔分离;侧脑室体部扩大、平行或体部脉络丛夹角缩小;侧脑室枕角扩大;第三脑室扩大、上移。合并灰质异位(3例)、脑裂畸形(2例)、蛛网膜囊肿(2例)、脂肪瘤(4例)、透明隔缺如(1例)、光滑脑(1例)、脑穿通畸形(3例)、丘脑融合(1例)和空洞脑(1例)。结论MRI可以直接显示胼胝体形态,是诊断胼胝体发育不全并颅内畸形的最佳方法。

Objective To explore the MRI diagnostic value in dysgenesis of the corpus callosum incorporate encephalic malformation. Materials and Methods The MR findings of 18 cases with dysgenesis of the corpus callosum incorporate encephalic malformation were retrospectively analyzed. Results The complete lack of the corpus callosum was found in 10 cases, partial lack of the.corpus callosum in 6 cases and thinning of the corpus caUosum in 2 cases. The MRI findings of dysgenesis of the corpus callosum included enlargment of interhemispheric fissure with approaching to the anterior part of the third ventricle（ 100% ） ; fiat straightness and separated frontal horns; separated interventricular foramina; nearly parallel body part of lateral ventricles or decreased angle between the choroids plexus of the ventricle; dilatation and elevation of the third ventricle; enlarged occipital horus. Accompanying congenital anomalies of the central nervous system were gray matter heterotopia（3 cases）, abnormalities of schizencephaly（2 cases）, arachnoid cyst（3 cases）, lipoma（4 cases）, lack of septum pellucidum （1 case） , smoothing cerebral gyri （1 case） , porencephaly（ 3 cases ） , thalamic fusion（ 1 case） , hollow cerebral gyri （ 1 case）. Conclusion MRI can directly observe the morphologic construction of corpus callosum, MRI is the best method to diagnose the dysgenesis of the corpus callosum incorporate encephalic malformation.