癫痫患者生活质量问卷-89中文版的信度和效度分析

Reliability and Validity of a Chinese Version of the Quality of Life in Epilepsy Inventory

目的：修订中文版成年癫痫患者生活质量问卷-89（QOLIE-89）,并分析其信度和效度.方法：将英文版QOLIE-89修订成中文版QOLIE-89.用QOLIE-89量表现场及信函调查成年癫痫患者204例,考察量表的重测信度、内部一致性信度、结构效度和实证效度.结果：QOL-89中文版重测信度相关系数为0.63～0.95（P＜0.001）,Cronbach α系数为0.72～0.99;探索性因素分析获得17个因子,累计解释总方差的71.91%;将17个因子归纳为生理、心理和社会功能三个维度,验证性因子分析证实了三维的量表结构（CMIN/DF=2.17,GFI＝0.98, AGFI=0.90, CFI=0.98,RMSEA=0.061）.从发作严重程度和药物副作用分析显示该量表具有良好的实证效度.结论：修订的QOLIE-89中文版与英文原版相似,具有良好的信度和效度,适合我国成年癫痫患者的生活质量的评价.

Objective： This study aimed to develop a Chinese version of Quality of life in Epilepsy Inventory （ QOLIE-89 ） and to confirm its psychometric properties. Methods： The original English version QOLIE-89 was adapted to Chinese language through a translation back-translation procedure. The assessment included 204 patients with epilepsy. The test-retest and internal consistency reliabilities, criterion validity and discriminative validity were assessed. Results： The test-retest reliability （Pearson＇s correlation coefficient） for Chinese version QOLIE-89 was 0. 63 -0. 95 and internal consistency reliability （ Cronbach＇s alpha） was 0. 76 -0. 92. The confirmatory factor analysis indicated that the Chinese version of QOLIE-89 was composed of three dimensions （ CMIN/DF = 2. 17, GFI = 0. 98, AG- FI =0. 90, CFI =0. 98, RMSEA =0. 061 ）, which were physiology, psychology and social function that including 17 factors obtained by exploration analysis , which can explained 71.91% of total variance. Spearman＇s rank correlations between Chinese version QOLIE-89 total score and QOLIE-31 total score was 0. 96 and domain scores were from 0. 86 - 1.00. QOLIE-89 items could be discriminated well between patients according to epileptic seizures severity and antiepileptic drug side effects. Conclusion： The psychometric properties of the Chinese version QOLIE-89 inventory are fairly good and similar to the American version and can be applied to assess quality of life for adult patients with epilepsy in China.