连续粪便隐血试验(胶体金法)在结直肠癌筛查中的临床研究

Colorectal Cancer Screening with Sequential Fecal Occult Blood Test

目的评价连续粪便隐血试验(Sequential Fecal Occult Blood Test,SFOBT)(胶体金法)结合电子结肠镜和病理学诊断在结直肠癌早期筛查中的应用价值。方法2006-10-01～2006-12-03,消化内科门诊就诊的60例40岁以上便秘或腹泻6个月以上患者,自愿接受胶体金法粪便隐血试验,连续3 d。阳性者行电子结肠镜检查,对可疑结肠组织进行病理标本采集。结果22例SFOBT阳性(22/60),阳性率为36.67%。其中,器质性病变者20例(20/22),结直肠癌2例(2/20),为全部筛查人群的3.33%,1例为Ducks A期,1例为Ducks B期,未见Ducks C期和D期。结论SFOBT是检出有手术切除机会结直肠癌的一种经济实用、相对可靠的筛查手段,适于在我国进行大范围的普查工作。

Objective To assess the application of Sequential Fecal Occult Blood Test （SFOBT） （Aurosol） combined with electronic colonoscope and pathological diagnosis in screening of colorectal cancer. Methods Sixty outpatients were undertaken the screening who had come to see doctors ince Oct. 1^st,2006 to Dec.3^nd,All of them were voluntary and at lest 40 - year - old. First they were performed a SFOBT（Aurosol）. Some of them who had got a positive result would undertake the electrical colonscope, and questionable colon tissue would be collected and checked. Results The positive rate of SFOBT is 36.67 %, 2 colorectal cancers had been found with a detection rate of 3.33 %. One was in the stage of Ducks A, the other was in Ducks B. Nobody was found in the stage of Ducks C or D. Conclusion SFOBT （Aurosol） is an economical, practical and quite sensitivity and reliability method to detect eoloreetal cancer in stage that exairesis can be carried out. And also it is adoptable to wide - ranging mass screening in our country.