人工流产后不孕与抗精子抗体的关系分析

Analysis of correlation between antisperm antibody and infertility after induced abortion

本文采用酶联免疫吸附试验（ELISA）对78例因人工流产后所引起的不孕症、140例非人工流产不孕症以及28例正常已婚育龄妇女进行血清抗精子抗体（AsAb）检测，结果3组AsAb的阳性率分别为33．33％、15．71％、3．57％。人工流产后不孕组血清中AsAb的阳性率显著高于非人工流产不孕组和正常已婚育龄妇女（P＜0．05）。提示由人工流产所引起的不孕症，在某些方面可能与免疫因素有关。文中还对人工流产后AsAb的产生和引起不孕的机理进行了讨论。子宫内膜的破损和炎症可能是AsAb产生的一个重要诱因。

Enzyme-linked immunosorbent assays (ELISA) were done on 78 cases of in fertility caused by induced abortion、140 cases of non-induced-abortion in fertility and 28 normal mar-ried women of child-bearing age who had been tested with serum antisperm antibody (AsAb). The results showed that their positive rates were 33. 33%、15. 71% and 3. 57% re-spectively. The AsAb positive rate in serum for those cases with in fertility caused by induced abortion was apparently higher than that for those cases with non-induced-abortion infertility and the normal group by statistics (P<0. 05). It is noted that certain factors of infertility caused by induced abortion may be related to immunity. The paper also dealt with infertility mechanism and formation of antisperm antibody after induced abortion. The damaged and in-flamed endometrium may be the main incentive to the formation of antisperm antibody.