先锋霉素珠链结合组织瓣转位在合并溃疡的慢性骨髓炎中的应用

Application of Cephalosporin Bead Chains and transferring the flap of tissue in treatment of chronic osteomyelitis complicating vomicose

目的探讨慢性骨髓炎组织缺损的治疗原则和方法。方法回顾分析我院自1999年至2005年对56例下肢合并溃疡的慢性骨髓炎彻底清除感染病灶置入先锋霉素珠链控制感染,同时应用植骨结合组织瓣转位修复骨与软组织缺损。术后随访1～4年,平均2.5年。结果1例失随访。所有病例中优38例;良17例.;无差。骨和软组织缺损达满意修复。结论先锋霉素珠链结合组织瓣转位可以消除死腔,并可在病变局部持续释放高浓度的抗生素控制感染,同时具有引流作用,明显提高了一期手术植骨和组织瓣移位修复重建骨髓炎组织缺损的成功率。简化和宿短了手术治疗过程,此方法在感染性骨与组织缺损的修复重建中有其独特的优越性。

Objective To evaluate the therapeutic principles and methods of the tissue defects in chronic osteomyelitis. Methods 56 cases of lower limbs chronic osteomyelitis complicating vomicose from 1997 to2005 were analyzed retrospectively. All cases were performed by clearing offthe infected part and inserting cephalosporin bead chains so as to prevent infection. At the same time, using bone graft and transferring the flap of tissue. At the meaning of following up of 2.5 （range 1-4） years. Results One case was lost following up. Among the 55 cases, there were 38 excellent, 17 fine, no poor. All tissue defects were repaired effectively. Conclusion Application ofcephalosporin bead chains and transferring the flap of tissue can get rid of caverna, and release high condensed anti-biotic continually in the pathological change area to control infection. Besides it helps the drainage functions, which promotes the rote of success of the operation, simplifying and shortening the process of the operation. This method has its advantage in the course of the repairing and reconstruction of infected bonds and the tissue defect.