小儿伤寒并溶血性尿毒症综合征临床观察

Clinical Observation of Children Typhoid and HUS(Hemolytic uremic syndrome)

目的了解小儿伤寒并溶血性尿毒症综合征(HUS)的临床特点、诊断要点,探讨其治疗方法及效果。方法对10例伤寒并溶血性尿毒症综合征患儿的临床表现、实验室检查、综合治疗措施及转归资料,进行综合分析。结果本组病例均为学龄前或学龄儿童,HUS 症状典型,伤寒症状以持续高热、消化道症状突出,明确诊断、综合治疗10 d 内血红蛋白上升,尿量正常,20d 内所有症状逐渐恢复。结论对小儿伤寒并溶血性尿毒症综合征采取综合治疗预后较好,与预后有关的因素是少尿期持续时间。激素治疗可阻止病情进展。

Objective To know the clinical characteristic and the main diagnosis of children typhoid with HUS, discussed the methods and effect of the treatments. Methods To analyze the clinical manifestation, lab examination, synthetic therapy and the change of disease data of 10 cases of children typhoid with HUS. Results All of the patients in this group were preschool age or school age child, they had the typical HUS symptoms, continuous fever hyperthermy and digestive tract symptoms. Then clear diagnosis was made, the hemoglobin was risen after 10 days treatment, urinary output was regular, all the symptoms returned to normal in 20 days. Conclusion Children typhoid with HUS could get a better prognosis after synthetic therapy, the relevant factors are the continuous time of oliguria period, hormone treatment could stop the illness development.