平肝祛痰化瘀治疗高血压伴肥胖30例临床研究

Treatment of Patients with Obesity and Hypertension by Calming Liver,Expelling Phlegm and Removing Blood Stasis

目的观察平肝祛痰化瘀治疗对高血压伴肥胖病人的临床疗效。方法60例原发性高血压伴肥胖病人随机分为平肝祛痰化瘀加尼群地平组(治疗组)和非诺贝特加尼群地平组(对照组),疗程均为30d。结果治疗组治疗前后比较,血压、症状积分、总胆固醇(TC)、三酰甘油(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、体重指数均有统计学意义(P<0.01);对照组治疗前后血压、症状积分、TC、TG、HDL-C比较有统计学意义(P<0.01或P<0.05);治疗后治疗组舒张压、症状积分、TC、LDL-C、体重指数与对照组比较有统计学意义(P<0.01或P<0.05)。结论平肝祛痰化瘀治疗高血压伴肥胖病人有较好疗效。

Objective To explore the treatment of patients （pts） with obesity and hypertension by calming liver, expelling phlegm and removing blood stasis. Methods Sixty pts with obesity and hypertension were divided randomly into the treatment group （ n = 30） treated by calming liver, expelling phlegm and removing blood stasis plus nitredipine and the control group （ n = 30） by fenofibrate and nitrendip- ine. Results After treatment, blood pressure, symptom, TC, TG, HDL- C, LDL- C and MBI were improved significantly in the treatment group （ P 〈 0.01 ）. Blood pressure, symptom, TC, TG, HDL - C were improved significantly in the control group（P 〈 0.01 or P 〈 0.05 ）. Diastolic pressure, symptom, TC, LDL- C, MBI was significant difference between the two group（P〈0.01 or P〈0.05）. Conclusion The method of calming liver, expelling phlegm and removing blood stasis could improve blood pressure, symptom, hyperlipemia and MBI in pts with obesity and hypertension.