绝经后妇女骨质疏松性椎体骨折与腰椎骨密度的关系

Relationship between vertebral osteoporotic fracture and bone mineral density of lumbar spine in postmenopausal women

目的探讨绝经后妇女骨质疏松性椎体骨折与腰椎骨密度的关系。方法选择骨质疏松性椎体骨折的绝经后妇女23例为骨折组,无椎体骨折的25例绝经后骨质疏松妇女为对照组。两组的年龄、绝经年限、身高、体重、体重指数差异无显著性,均行胸腰椎正侧位X线摄片。用双能X线吸收仪(DXA)测量的腰椎(L2-4)前后位骨密度(BMD)、骨矿含量(BMC)和T值。结果骨折组BMD、BMC和T值均低于对照组(P<0.01)。结论腰椎BMD降低与绝经后妇女的骨质疏松性椎体骨折相关。绝经后骨质疏松妇女应重视BMD变化,预防椎体骨折的发生。

Objective To evaluate the relationship between vertebral osteoporotic fracture and bone mineral density （BMD） of lumbar spine in postmenopausal women. Methods Twenty-three postmenopausal women with vertebral osteoporotic fractures and the other 25 postmenopausal women without vertebral fractures as control were included. All the vertebral fractures were confirmed by posterior-anterior and lateral spine radiographs. The age, menopause duration, height, body weight and body mass index were not significantly different between facture group and control group. The BMD, bone mineral content （BMC） and T-score at the lumbar spine （L2-4） were measured by dual energy X-ray absorptiometry in both groups. Results BMD, BMC and T-score of L2-4 in fracture group were significantly lower than those in the control group （all P 〈 0.01 ）. Conclusion Lowered BMD of the lumbar vertebrae is closely connected to vertebral osteoporotic fracture. It is necessary to pay more attention to the change of BMD and the prevention of vertebral fracture in postmenopausal osteoporotic women.